Article

High diversity in the regulatory region of Stx-converting bacteriophage genomes

2021-11-24

Abstract excerpt

<h4>ABSTRACT</h4> Shiga toxin (Stx) is the major virulence factor of enterohemorrhagic Escherichia coli (EHEC), and the stx genes are carried by temperate bacteriophages (Stx phages). The switch between lysogenic and lytic life cycle of the phage, which is crucial for Stx production and for severity of the disease, is regulated by the CI repressor. CI maintain latency by preventing transcription of the replicat...

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Literature Corpus work: c971c351-5076-5c39-8bff-d4919218520e
DOI: 10.1101/2021.11.24.469858

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