Article

Structured Schemas for Provenance-Rich, LLM-Assisted QSP Model Calibration

2026-03-09

Abstract excerpt

Quantitative systems pharmacology (QSP) models require calibration data from literature, yet manual curation is inconsistently documented and large language model (LLM) extraction can hallucinate values and fabricate citations. We present MAPLE (Model-Aware Parameterization from Literature Evidence), which uses structured validation schemas as a collaboration interface between LLMs and modelers. Two schemas span t...

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Literature Corpus work: c9545a4c-adb6-54af-8aab-3c0bf077a6d5
DOI: 10.64898/2026.03.05.709623

Open publication

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