Article

Auditable LLM Curation of Clinical Notes Refines GLP-1 Initiation, Persistence Ascertainment and Compounding Use Beyond Prescription Records

2026-06-09

Abstract excerpt

Real-world benefit from incretin-based therapies depends on actual treatment initiation and sustained exposure, yet structured prescription records may capture prescribing intent rather than confirmed use. Using a large federated, de-identified U.S. EHR platform spanning over 29 million patients, we analyzed patterns of GLP1-RA initiation, persistence, and compounding from clinical notes using an evidence-linked l...

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Literature Corpus work: 777f7e50-8309-57ed-a798-11a80ca4a782
DOI: 10.20944/preprints202606.0682.v1

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