Article

Computational analysis revealing that K634 and T681 mutations modulate the 3D-structure of PDGFR-β and lead to sunitinib resistance

2017-01-01

Abstract excerpt

Platelet-derived growth factor receptor-beta (PDGFR-β) is expressed by endothelial cells (ECs) of tumor-associated blood vessels and regulates primarily early hematopoiesis.

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Literature Corpus work: c92b858a-9069-53c8-ac02-0f328d1f8515
DOI: 10.1039/c7ra01305a

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