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Article

A validated antibody toolbox for ALS research

2025-09-17

Abstract excerpt

A substantial fraction of amyotrophic lateral sclerosis (ALS)-associated proteins remain poorly characterized, in part because of the limited availability of validated research antibodies. We established knockout (KO)-based antibody characterization workflows and demonstrated that widely used antibodies against the major ALS-associated protein C9orf72 lacked specificity (Laflamme et al., 2019). We subsequently sca...

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Identifiers and source

Literature Corpus work
c914addb-d084-5189-ac82-94428d925087
DOI
10.1101/2025.09.14.676084
Open publication

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A validated antibody toolbox for ALS researchDOI 10.1101/2025.09.14.676084
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