Article

Anti-Signal Recognition Particle-Positive Immune-Mediated Necrotizing Myopathy with Acute Inpatient Myocarditis and Pharyngeal Involvement in a Young Adult: A Case Highlighting the Importance of Early Biologic Escalation – A Case Report

2026-08-28

Abstract excerpt

<title>Abstract</title> <p>Background Immune-mediated necrotizing myopathy (IMNM) is a rare and clinically severe subtype of idiopathic inflammatory myopathy, characterised by predominant myofibre necrosis with a paucity of lymphocytic infiltration. Anti-signal recognition particle (anti-SRP)-positive IMNM represents a particularly aggressive disease phenotype, frequently resistant to corticosteroid monotherapy...

Topics

Open a Topic to create a Post that cites this publication.

Uncategorized literature

Identifiers and source

Literature Corpus work: c8b9372a-b093-5384-9200-08b77a13cbfe
DOI: 10.21203/rs.3.rs-10398087/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Click a neighbor to travelStep 1 · 12 closest

Anti-Signal Recognition Particle-Positive Immune-Mediated Necrotizing Myopathy with Acute Inpatient Myocarditis and Pharyngeal Involvement in a Young Adult: A Case Highlighting the Importance of Early Biologic Escalation – A Case ReportDOI 10.21203/rs.3.rs-10398087/v1Read

Necrotising myopathy associated with anti-signal recognition particle (anti-SRP) antibody.Semantic proximity Read

Clinical Characteristics of Immune-Mediated Necrotizing Myopathy with Autoantibodies Recognizing the Signal Recognition Particle: A Retrospective Study of a Chinese CohortSemantic proximity Read

Anti-mitochondrial antibody-positive myositis: A systematic review of 123 casesSemantic proximity Read

Clinical phenotypes and long-term outcomes of anti-SRP versus anti-HMGCR immune-mediated necrotising myopathy: a 13-year single-centre study.Semantic proximity Read

The pathogenesis of anti-signal recognition particle necrotizing myopathy: A ReviewSemantic proximity Read

Treatment experience of Taiwanese patients with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase myopathy.Semantic proximity Read

Inflammatory myopathy associated with anti-mitochondrial antibodies: A distinct phenotype with cardiac involvement.Semantic proximity Read

Clinical-pathologic classification of anti-HMGCR-positive immune-mediated necrotizing myopathySemantic proximity Read

Idiopathic inflammatory myopathies: current trends in pathogenesis, clinical features, and up-to-date treatment recommendations.Semantic proximity Read

Distinct phenotype and prognosis of immune-mediated necrotizing myopathy based on clinical-serological-pathological classification.Semantic proximity Read

Autoimmune myopathies: autoantibodies, phenotypes and pathogenesis.Semantic proximity Read

Thymoma-Associated Paraneoplastic Syndromes: Concurrent Inflammatory Myopathy and Guillain–Barré Syndrome Complicated by Reverse Takotsubo CardiomyopathySemantic proximity Read