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Article

Distinct phenotype and prognosis of immune-mediated necrotizing myopathy based on clinical-serological-pathological classification.

Rheumatology (Oxford, England) - 1 Apr 2025

Yang Hongxia, Zhang Lining, Tian Xiaolan, Li Wenli, Liu Qingyan, Peng Qinglin, Jiang Wei, Wang Guochun, Lu Xin

Abstract excerpt

OBJECTIVE: The aim of the study was to investigate the characteristics and prognosis of patients with immune-mediated necrotizing myopathy (IMNM) based on clinical, serological and pathological classification. METHODS: A total of 138 patients with IMNM who met the 2018 European Neuromuscular Center criteria for IMNM including 62 anti-SRP, 32 anti-HMGCR-positive and 44 myositis-specific antibody-negative were...

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Identifiers

PMID: 39029922
DOI: 10.1093/rheumatology/keae361

Genes

CD4
HMGCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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