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Article

Role of Melatonin in the Regulation of Pain

1 Feb 2020

Abstract excerpt

Melatonin is a pleiotropic hormone synthesized and secreted mainly by the pineal gland in vertebrates. Melatonin is an endogenous regulator of circadian and seasonal rhythms. Melatonin is involved in many physiological and pathophysiological processes demonstrating antioxidant, antineoplastic, anti-inflammatory, and immunomodulatory properties. Accumulating evidence has revealed that melatonin plays an important...

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PMID: 32104055
DOI: 10.2147/jpr.s228577

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