Article

Bayesian modeling of BAC firing as a mechanism for apical amplification in neocortical pyramidal neurons

2019-04-15

Abstract excerpt

Pyramidal cells in layer 5 of the neocortex have two distinct integration sites. These cells integrate inputs to basal dendrites in the soma while integrating inputs to the tuft in a site at the top of the apical trunk. The two sites communicate by action potentials that backpropagate to the apical site and by backpropagation-activated calcium spikes (BAC firing) that travel from the apical to the somatic site. Si...

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Literature Corpus work: c8a76f50-fa60-5a80-afa0-d96685497c63
DOI: 10.1101/604066

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