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Presynaptic temporal dynamics flexibly set input weights in the mouse escape circuit

2026-05-20

Abstract excerpt

<h4>Summary</h4> Animals facing threat must integrate multiple streams of information — about danger, environment, and internal state — into a time-pressured escape decision. In mice, this computation is performed by glutamatergic neurons of the dorsal periaqueductal grey (dPAG), but how their convergent long-range inputs combine to drive flexible decisions is unknown. Here we find that the functional weight of e...

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Literature Corpus work
033725fe-e4d9-5f32-a655-d237c4953fb6
DOI
10.64898/2026.05.18.724906
Open publication

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Presynaptic temporal dynamics flexibly set input weights in the mouse escape circuitDOI 10.64898/2026.05.18.724906
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