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Article

Development and Characterisation of an in vitro Model of Wallerian Degeneration

10 Jul 2020

Abstract excerpt

Following peripheral nerve injury, a sequence of events termed Wallerian degeneration (WD) takes place at the distal stump in order to allow the regenerating axons to grow back towards the target organs. Schwann cells (SCs) play a lead role in this by initiating the inflammatory response attracting macrophages and immune cells, as well as producing neurotrophic signals that are essential for nerve regeneration....

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PMID: 32754584
DOI: 10.3389/fbioe.2020.00784

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