Article

Hypothetical gene <i>Rv0495c</i> regulates redox homeostasis in <i>Mycobacterium tuberculosis</i>

2023-08-22

Abstract excerpt

Mycobacterium tuberculosis (Mtb) has evolved sophisticated surveillance mechanisms to regulate and neutralize redox imbalances and associated lethal consequences. Failing this, the accumulated ROS induces toxicity by oxidizing a variety of biological molecules including proteins, nucleic acids and lipids. In the present study we identified Mtb’s Rv0495c gene as an important regulator of oxidized cytosolic environ...

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Literature Corpus work: c84b5443-bb98-57d8-a05e-8d1add1720ea
DOI: 10.1101/2023.08.22.554105

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