Article

Local Delivery of Bcar3 siRNA by Nano-Self-Assembly for Treating Pulmonary Fibrosis via Blocking the Interaction of Macrophages and Fibroblasts

2023-08-03

Abstract excerpt

<h4>Background: </h4> Idiopathic pulmonary fibrosis (IPF) is a life-threatening progressive interstitial lung disease with limited therapeutic options, characterized by macrophage infiltration and fibroblast activation in response to chronic lung injury. Specifically, the interaction of macrophages and fibroblasts is critical for facilitating IPF progression. However, no valuable therapeutic strategy has been prop...

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Literature Corpus work: c8475c50-bea0-5ba5-93df-7f67e83b570a
DOI: 10.21203/rs.3.rs-3212738/v1

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