Article

Deep longitudinal lower respiratory tract microbiome profiling reveals genome-resolved functional and evolutionary dynamics in critical illness

2023-11-09

Abstract excerpt

<title>Abstract</title> <p>The lower respiratory tract (LRT) microbiome impacts human health, especially among critically ill patients. However, comprehensive characterizations of the LRT microbiome remain challenging. We developed an efficient chelex100-based low-biomass microbial-enrichment method (CMEM) that enables the efficient deep metagenomic profiling of LRT samples to recover near-complete microbial geno...

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Literature Corpus work: c83f861f-6861-5adb-93ff-62049d244e5c
DOI: 10.21203/rs.3.rs-3494655/v1

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