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Longitudinal multicompartment characterization of host-microbiota interactions in patients with acute respiratory failure

3 Jun 2024

Abstract excerpt

Critical illness can significantly alter the composition and function of the human microbiome, but few studies have examined these changes over time. Here, we conduct a comprehensive analysis of the oral, lung, and gut microbiota in 479 mechanically ventilated patients (223 females, 256 males) with acute respiratory failure. We use advanced DNA sequencing technologies, including Illumina amplicon sequencing...

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PMID: 38830853
DOI: 10.1038/s41467-024-48819-8

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