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Detection of Bacterial Pathogens from Broncho-Alveolar Lavage by Next-Generation Sequencing

20 Sept 2017

Abstract excerpt

The applications of whole-metagenome shotgun sequencing (WMGS) in routine clinical analysis are still limited. A combination of a DNA extraction procedure, sequencing, and bioinformatics tools is essential for the removal of human DNA and for improving bacterial species identification in a timely manner. We tackled these issues with a broncho-alveolar lavage (BAL) sample from an immunocompromised patient who had...

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PMID: 28930150
DOI: 10.3390/ijms18092011

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