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Comprehensive Single-Cell Transcriptomic Profiling Identifies Molecular Subtypes and Prognostic Biomarkers in Esophageal Squamous Cell Carcinoma: Implications for Targeted Therapy

2023-10-03

Abstract excerpt

<h4>Background: </h4> Esophageal squamous cell carcinoma (ESCC) is a genetically heterogeneous disease with poor clinical outcomes. Identification of biomarkers linked to DNA replication stress may enable improved prognostic risk stratification and guide therapeutic decision making. We performed integrated single-cell RNA sequencing and computational analyses to define the molecular determinants and subtypes under...

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Literature Corpus work: c837c5b1-2eac-5c18-a828-a34f6dc4f88f
DOI: 10.21203/rs.3.rs-3313878/v1

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