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Dissecting the single-cell transcriptome network underlying esophagus non-malignant tissues and esophageal squamous cell carcinoma

27 Jun 2021

Abstract excerpt

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is among the most prevalent causes of cancer-related death in adults. Tumor microenvironment (TME) has been associated with therapeutic failure and lethal outcomes for patients. However, published reports on the heterogeneity and TME in ESCC are scanty. METHODS: Five tumor samples and five corresponding non-malignant samples were subjected to scRNA-seq...

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PMID: 34192657
DOI: 10.1016/j.ebiom.2021.103459

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