Article

SLFN11 captures cancer-immunity interactions associated with platinum sensitivity in ovarian cancer

2020-05-26

Abstract excerpt

Large independent analyses on cancer cell lines followed by functional studies have identified Schlafen 11 (SLFN11), a putative DNA/RNA helicase, as the strongest predictor of sensitivity to DNA-damaging agents. However, its role as a prognostic biomarker is undefined, partially due to the lack of validated methods to score SLFN11 in human tissues. Here, we implemented a pipeline to quantify SLFN11 in human cancer...

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Literature Corpus work: c80478eb-8151-5ecf-9852-f3d7f6753253
DOI: 10.1101/2020.05.22.110593

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