Article
SLFN11 is a general target for enhancing the sensitivity of cancer to chemotherapy (DNA-damaging agents)
16 May 2019
Abstract excerpt
In patients with cancer, drug tolerance often occurs during the use of chemotherapy drugs, seriously affecting patient prognosis and survival. Therefore, scientists began to study the factors that affect chemotherapy drug sensitivity, and the high correlation between Schlafen-11 (SLFN11) and sensitivity to chemical drugs (mainly DNA-damaging agents, DDAs) has received increasing attention since it was discovered...
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