Article

Molecular dynamics study of differential effects of serotonin-2A-receptor (5-HT2AR) modulators

2025-03-28

Abstract excerpt

The serotonin-2A receptor (5-HT 2A R) is an interesting target for drug design in the context of antidepressants that might have a rapid onset of action and/or be effective in treatment-resistant cases. The main challenge, however, is that the activation of this receptor can provoke hallucinations. Recent studies have shown that activating the receptor with certain (partial) agonists could potentially give rise t...

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Literature Corpus work: c7f8e654-b2ca-59dc-a5a2-8120632ccfa2
DOI: 10.1101/2025.03.27.645663

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