Article
[Animal models of hereditary diseases].
La Revue du praticien - 15 Jan 1997
Montagutelli X, Guénet J L
Abstract excerpt
A large number of genetic diseases are found both in humans and in one or several animal species. The mouse is a species of choice since, in addition to hundreds of spontaneous mutations which have been described, it is now possible to produce at will a mutation in any gene. This strategy has been used to generate genetically engineered mice which carry genetic defects found in human molecular pathology. Animal...
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