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Article

Era of the 4D animal model.

Animal models and experimental medicine - 1 Apr 2023

Zhang Lihong, Guo Jindan, Liu Jiangning

Abstract excerpt

Revealing the entire dynamics of pathogenesis is critical for understanding, preventing and treating human disease but is limited by systematic clinical sampling. This drawback can be overcome with animal model studies. Recent advances in phenotyping, omics and bioinformatics technologies promote the development of the 4D animal model to simulate and digitally display the spatiotemporal landscapes of phenotypes...

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Identifiers

PMID: 36852490
DOI: 10.1002/ame2.12306
PMCID: PMC10158943

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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