Article

IGPR-1 is phosphorylated on the immunoreceptor tyrosine-based motif, stimulates AKT pathway and supports melanoma growth

2024-08-19

Abstract excerpt

<h4>ABSTRACT</h4> Melanoma is a lethal form of skin cancer that impacts one out of every five Americans and ranks as the fifth most prevalent cancer among men and women in the United States. Immunoglobulin (Ig) and Proline-rich Receptor-1 (IGPR-1, also called TMIGD2/CD28H) is closely related to immune checkpoint, CD28/PDL1 family receptors. It controls important cellular processes including, immune cell regulatio...

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Literature Corpus work: c7826b0c-9a01-5a89-90c0-61432f117eea
DOI: 10.1101/2024.08.19.608690

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