Article

MicroRNA-378a-3p Modulates Inflammatory Responses of Keratinocytes to Atopic Dermatitis-Related Cytokines or <i>Staphylococcus aureus</i>

2026-03-18

Abstract excerpt

miR-378a-3p has been reported to be upregulated in the lesional skin of patients with atopic dermatitis (AD); however, its function in AD remains unclear. Here, we demonstrate that miR-378a-3p expression is induced by IL-4 and live Staphylococcus aureus ( S. aureus ) in normal human epidermal keratinocytes (NHEKs) cultured in proliferative conditions or in a 3D epidermal culture model. Transcriptomic profiling a...

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Literature Corpus work: c74bc757-21fc-5233-92f8-d23291dc3ae9
DOI: 10.64898/2026.03.16.711984

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