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Article

miR ‐378a regulates keratinocyte responsiveness to interleukin‐17A in psoriasis*

8 Mar 2022

Abstract excerpt

BACKGROUND: Psoriasis is an immune-mediated inflammatory skin disease, in which an interplay between infiltrating immune cells and keratinocytes sustains chronic skin inflammation. Interleukin (IL)-17A is a key inflammatory cytokine in psoriasis and its main cellular targets are keratinocytes. OBJECTIVES: To explore the role of miR-378a in psoriasis. METHODS: Keratinocytes obtained from psoriatic skin and healthy...

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PMID: 35257359
DOI: 10.1111/bjd.21232

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