Article

Single Cell Sequencing of Human Langerhans Cells Identifies Altered Gene Expression Profiles in Patients with Atopic Dermatitis

2024-05-09

Abstract excerpt

Atopic dermatitis (AD) is characterized by dysregulated T cell immunity and skin microbiome dysbiosis with predominance of Staphylococcus aureus ( S. aureus ). Emerging evidence suggests a role for S. aureus in exacerbating AD skin inflammation. We have previously shown that specific glycosylation of S. aureus cell wall structures amplifies skin inflammation through interaction with Langerhans cells (LCs). However...

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Literature Corpus work: 5c641dbf-70c2-5cdf-9cbc-623e6836878b
DOI: 10.1101/2024.05.06.24306801

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