Article

LimROTS: A Hybrid Method Integrating Empirical Bayes and Reproducibility-Optimized Statistics for Robust Differential Expression Analysis

2025-02-08

Abstract excerpt

<h4>Motivation</h4> Differential expression analysis plays a vital role in omics research enabling precise identification of features that associate with different phenotypes. This process is critical for uncovering biological differences between conditions, such as disease versus healthy states. In proteomics, several statistical methods have been used, ranging from simple t-tests to more advanced methods like l...

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Literature Corpus work: c743114a-ce37-56e0-b52d-1d015ed028d4
DOI: 10.1101/2025.02.06.636801

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