Article

MINT: A multivariate integrative method to identify reproducible molecular signatures across independent experiments and platforms

2016-08-22

Abstract excerpt

<h4>Background</h4> Molecular signatures identified from high-throughput transcriptomic studies often have poor reliability and fail to reproduce across studies. One solution is to combine independent studies into a single integrative analysis, additionally increasing sample size. However, the different protocols and technological platforms across transcriptomic studies produce unwanted systematic variation that...

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Literature Corpus work: 0ec0e2bb-4317-589f-9957-6e1f6652ebd5
DOI: 10.1101/070813

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