Article

Integrated host-microbe metagenomics for sepsis diagnosis in critically ill adults

2022-07-17

Abstract excerpt

Sepsis is a leading cause of death, and improved approaches for disease diagnosis and detection of etiologic pathogens are urgently needed. Here, we carried out integrated host and pathogen metagenomic next generation sequencing (mNGS) of whole blood (n=221) and plasma RNA and DNA (n=138) from critically ill patients following hospital admission. We assigned patients into sepsis groups based on clinical and microb...

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Literature Corpus work: c730e2d7-6a1f-546b-906b-5948ae149f51
DOI: 10.1101/2022.07.16.22277700

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