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Halofantrine protects photoreceptors in multiple models of retinal degeneration

2026-05-13

Abstract excerpt

<title>Abstract</title> <p>Inherited retinal degenerative diseases (IRDs), including retinitis pigmentosa (RP) and Leber congenital amaurosis (LCA), cause progressive vision impairment due to photoreceptor degeneration. We previously demonstrated the protective effects of reserpine in models of CEP290-LCA and in the female Rhodopsin-P23H rat model of autosomal dominant RP. Given that reserpine is limited by side...

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Literature Corpus work
c70eac54-9cdb-5f62-9084-f97017aca983
DOI
10.21203/rs.3.rs-9511432/v1
Open publication

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Halofantrine protects photoreceptors in multiple models of retinal degenerationDOI 10.21203/rs.3.rs-9511432/v1
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