Article
Sex differences in nociceptor translatomes contribute to divergent prostaglandin signaling in male and female mice
2020-08-03
Abstract excerpt
<h4>ABSTRACT</h4> <h4>Background</h4> There are clinically relevant sex differences in acute and chronic pain mechanisms, but we are only beginning to understand their mechanistic basis. Transcriptome analyses of rodent whole dorsal root ganglion (DRG) have revealed sex differences, mostly in immune cells. We examined the transcriptome and translatome of the mouse DRG with the goal of identifying sex differences...
Topics
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- Cancer, Stress, Anesthesia, and Immune Response
- Exercise and Physiological Responses
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Hereditary Neurological Disorders
- Inflammatory mediators and NSAID effects
- Ion channel regulation and function
- Pain Mechanisms and Treatments
- Pharmacological Effects of Natural Compounds
Identifiers and source
- Literature Corpus work
- c6fbae48-255a-5ff3-ac61-cc801ef5a359
- DOI
- 10.1101/2020.07.31.231753
