Article

Germline gene de-silencing by a transposon insertion is triggered by an altered landscape of local piRNA biogenesis

2020-06-26

Abstract excerpt

Transposable elements (TE) are selfish genetic elements that can cause harmful mutations. In Drosophila , it has been estimated that half of all spontaneous visible marker phenotypes are mutations caused by TE insertions. Because of the harm posed by TEs, eukaryotes have evolved systems of small RNA-based genome defense to limit transposition. However, as in all immune systems, there is a cost of autoimmunity and...

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Literature Corpus work: c6e4492d-38b1-59e0-9d85-ddfbdc322c41
DOI: 10.1101/2020.06.26.173187

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