Article

Protein-Protein Interactions Shape Genomic Autoimmunity in the Adaptively-Evolving Rhino-Deadlock-Cutoff (RDC) Complex

2020-11-13

Abstract excerpt

<h4>ABSTRACT</h4> The piRNA pathway is a genomic defense system that controls the movement of transposable elements (TEs) through transcriptional and post-transcriptional silencing. While TE defense is critical to ensuring germline genome integrity, it is equally critical that the piRNA pathway avoids autoimmunity in the form of silencing host genes. Ongoing cycles of selection for expanded control of invading TE...

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Literature Corpus work: 8e4c3471-fc64-59e0-884e-8dcc7ba24027
DOI: 10.1101/2020.11.12.380154

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