Article

The critical role of isomiRs in accurate differential expression analysis of miRNA-seq data

2024-03-31

Abstract excerpt

MicroRNAs (miRNAs) are crucial for the regulation of gene expression and are promising biomarkers and therapeutic targets. miRNA isoforms (isomiRs) differ in their start/end offsets, which can impact the target gene selection and non-canonical function of the miRNA species. In addition, isomiRs frequently differ in their expression patterns from their parent miRNAs, yet their roles and tissue-specific responses ar...

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Literature Corpus work: c65d5fc9-4725-542e-b449-b714327ad7f3
DOI: 10.1101/2024.03.28.587190

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