Article

Autoantibodies Targeting Angiotensin Converting Enzyme 2 Are Prevalent and Not Induced by SARS-CoV-2 Infection

2024-11-18

Abstract excerpt

Clinical outcomes resulting from SARS-CoV-2 infection vary widely, ranging from asymptomatic cases to the development of mild to severe respiratory illness, and in some instances, chronic lingering disease and mortality. The underlying biological mechanisms driving this wide spectrum of pathogenicity among certain individuals and demographics remain elusive. Autoantibodies have emerged as potential contributors to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c65cc73a-ef96-53d8-ab05-7230f386a7c9
DOI: 10.1101/2024.11.18.24317488

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Autoantibodies Targeting Angiotensin Converting Enzyme 2 Are Prevalent and Not Induced by SARS-CoV-2 InfectionDOI 10.1101/2024.11.18.24317488Read

Discriminating promiscuous from target‐specific autoantibodies in COVID‐19Semantic proximity Read

Predominance of Distinct Autoantibodies in Response to SARS-CoV-2 InfectionSemantic proximity Read

Angiotensin-converting enzyme 2—at the heart of the COVID-19 pandemicSemantic proximity Read

ACE-2-like Enzymatic Activity in Anti-SARS-CoV-2 Spike Protein Monoclonal AntibodiesSemantic proximity Read

ACE2 partially dictates the host range and tropism of SARS-CoV-2Semantic proximity Read

Emerging roles of SARS-CoV-2 Spike-ACE2 in immune evasion and pathogenesisSemantic proximity Read

A comprehensive investigation of the mRNA and protein level of ACE2, the putative receptor of SARS-CoV-2, in human tissues and blood cellsSemantic proximity Read

Downregulation of Membrane-bound Angiotensin Converting Enzyme 2 (ACE2) Receptor has a Pivotal Role in COVID-19 ImmunopathologySemantic proximity Read

Limited cross-variant immune response from SARS-CoV-2 Omicron BA.2 in naïve but not previously infected outpatientsSemantic proximity Read

SARS-CoV-2, ACE2 expression, and systemic organ invasionSemantic proximity Read

ACE2 and COVID-19 Susceptibility and SeveritySemantic proximity Read

A novel rapid detection for SARS-CoV-2 spike 1 antigens using human angiotensin converting enzyme 2 (ACE2)Semantic proximity Read