Article
Organization of uroplakin subunits: transmembrane topology, pair formation and plaque composition
2001-02-26
Abstract excerpt
The apical surfaces of urothelial cells are almost entirely covered with plaques consisting of crystalline, hexagonal arrays of 16nm uroplakin particles. Although all four uroplakins, when SDS-denatured, can be digested by chymotrypsin, most uroplakin domains in native urothelial plaques are resistant to the enzyme, suggesting a tightly packed structure. The only exception is the C-terminal, cytoplasmic tail of UP...
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Identifiers and source
- Literature Corpus work
- c6463721-8c5b-52a4-8595-e87491b304ee
- DOI
- 10.1042/bj3550013