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Article

Uroplakin Gene Expression by Normal and Neoplastic Human Urothelium

1 Dec 1998

Abstract excerpt

cDNA sequences for human uroplakins UPIa, UPIb, UPII, and UPIII were cloned and used to investigate uroplakin transcription by normal and neoplastic urothelial cells. Normal urothelium expressed mRNA for all four uroplakins, although UPIII could be detected only by ribonuclease protection assay. By in situ hybridization, UPIa and UPII were confined to superficial cells and UPIb was also expressed by intermediate...

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PMID: 9846985
DOI: 10.1016/s0002-9440(10)65709-4

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