Article

Convergent depression of activity-dependent bulk endocytosis in rodent models of autism spectrum disorders

2024-10-12

Abstract excerpt

The key pathological mechanisms underlying autism spectrum disorders (ASDs) remain relatively undetermined, potentially due to the heterogenous nature of the condition. Targeted studies of a series of monogenic ASDs have revealed postsynaptic dysfunction as a central conserved mechanism. Presynaptic dysfunction is emerging as an additional disease locus in neurodevelopmental disorders, however it is unclear whethe...

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Literature Corpus work: c631ed05-28d0-5ba3-be6e-7bc8596db855
DOI: 10.1101/2024.10.10.617607

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