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Article

Targeted Therapy Improves Real-World Survival in Patients with Molecularly Matched Advanced Biliary Tract Cancer

2025-10-12

Abstract excerpt

<title>Abstract</title> <p>Molecular profiling reveals that up to 40% of advanced biliary tract cancers (BTCs) harbor actionable genomic alterations amenable to matched targeted therapies. However, conventional trial designs typically evaluate these agents in pretreated populations, resulting in approvals for later-line use. Notably, 25–44% of patients with advanced BTC may become ineligible for treatment after f...

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Literature Corpus work
c6244175-5d52-5751-a141-9b3c045653a8
DOI
10.21203/rs.3.rs-7744614/v1
Open publication

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Targeted Therapy Improves Real-World Survival in Patients with Molecularly Matched Advanced Biliary Tract CancerDOI 10.21203/rs.3.rs-7744614/v1
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