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Article

Matching genomic molecular aberrations with molecular targeted agents: Are biliary tract cancers an ideal playground?

European journal of cancer (Oxford, England : 1990) - 1 Aug 2017

Verlingue Loic, Hollebecque Antoine, Boige Valérie, Ducreux Michel, Malka David, Ferté Charles

Abstract excerpt

Biliary tract cancers (BTCs) are a heterogeneous group of tumours with geographical discrepancies in terms of incidence and risk factors. However, a convergent genomic and epigenetic mutational landscape emerges from the genome-wide screens of BTCs in South East Asia, Latin America and in the Western World. Specificities are observed for some alterations and anatomical subtypes: frequent fibroblast growth factor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28628842
DOI: 10.1016/j.ejca.2017.05.006

Genes

IDH1
BTC
ERBB2
FGFR2

Provenance

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