Article

Hetero-multicellular stromal cells incorporate into scaffold-free 3D cultures of epithelial cancer cells to drive invasion

2025-01-24

Abstract excerpt

<h4>ABSTRACT</h4> Breast cancer (BC) is the second leading cause of cancer-related death among women in the U.S. Organoid models of solid tumors have been shown to faithfully recapitulate aspects of cancer progression such as proliferation and invasion. Although patient-derived organoids (PDOs) and patient-derived xenograft organoids (PDXOs) are pathophysiologically relevant, they are costly to propagate, difficu...

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Literature Corpus work: c61d5f74-9df6-5391-8a8c-828f5060d237
DOI: 10.1101/2025.01.21.634082

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