Article

From trash to treasure: detecting unexpected contamination in unmapped NGS data

2017-09-06

Abstract excerpt

Standard procedures for NGS data analysis involve a pre-processing step of reads quality assessment, followed by the alignment of the filtered reads to a reference genome. Typically the amount of reads that correctly maps to the specific reference genome ranges between 70% and 90%, leaving in some cases a consistent fraction of unmapped sequences. Investigating the reasons of this discrepancy may provide relevant...

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Literature Corpus work: c5f44bda-dcc6-5177-bcd9-496825d10820
DOI: 10.7287/peerj.preprints.3230v1

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