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Anaerobic gut bacterial metabolites alter morphology and survival of neurons and glia in a hippocampal culture model of Parkinson’s Disease

2026-02-23

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> : Parkinson’s disease (PD) is associated with alpha-synuclein (α-syn) accumulation and spread. Recent evidence suggests a connection between PD and gastrointestinal changes early in the disease process due to host-bacterial interactions and association between the microbiome and PD pathology. <bold>Methods</bold> : Supernatants (SNs) from 16 bacterial strain...

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Literature Corpus work
c58b1fe6-cf00-5977-a351-1a34449462a9
DOI
10.21203/rs.3.rs-8852210/v1
Open publication

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Anaerobic gut bacterial metabolites alter morphology and survival of neurons and glia in a hippocampal culture model of Parkinson’s DiseaseDOI 10.21203/rs.3.rs-8852210/v1
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