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<i>Faecalibacterium prausnitzii</i> , depleted in the Parkinson’s disease microbiome, improves motor deficits in α-synuclein overexpressing mice

2025-09-21

Abstract excerpt

Gut microbiome composition is altered in Parkinson’s disease (PD), a neurodegenerative disorder characterized by motor dysfunction and frequently accompanied by gastrointestinal (GI) symptoms. Notably, microbial taxa with anti-inflammatory properties are consistently depleted in PD patients compared to controls. To explore whether specific gut bacteria may be disease-protective, we assembled a microbial consortium...

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Literature Corpus work
30af4bb2-8a5d-5855-9996-fa162aa80f28
DOI
10.1101/2025.09.18.677192
Open publication

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<i>Faecalibacterium prausnitzii</i> , depleted in the Parkinson’s disease microbiome, improves motor deficits in α-synuclein overexpressing miceDOI 10.1101/2025.09.18.677192
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