Article
Exome-wide association study reveals 7 functional variants associated with ex-vivo drug response in acute myeloid leukemia patients
2023-08-04
Abstract excerpt
Acute myeloid leukemia (AML) is a rare aggressive blood cancer without any long-term cure. Further, due to the extreme molecular heterogeneity of the disease, drug treatment response varies from patient to patient. The variability of drug response can cause unnecessary treatment in more than half of the patients with no or partial therapy responses leading to severe side effects, economic as well as time loss. Und...
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Identifiers and source
- Literature Corpus work
- c537c779-6573-5814-ba3a-d5fa765d91fe
- DOI
- 10.1101/2023.08.02.23290523