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Single and 2-dose vaccinations with MVA-BN<sup>®</sup> induce durable B cell memory responses in healthy volunteers that are comparable to older generation replicating smallpox vaccines

2022-09-09

Abstract excerpt

While the MVA-BN vaccine has been proven protective against smallpox and monkeypox, the long-term immunological persistence or booster effect has not been described. In this set of clinical studies, participants who had never been immunized against smallpox were randomized to receive, 4 weeks apart: 2 placebo vaccinations (PBO group, N =181); 1 MVA-BN vaccination followed by placebo(1×MVA group, N =181); or 2 MVA-...

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Literature Corpus work
c518de20-2e75-5076-bbae-5909c5d8bc15
DOI
10.1101/2022.09.07.22279689
Open publication

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Single and 2-dose vaccinations with MVA-BN<sup>®</sup> induce durable B cell memory responses in healthy volunteers that are comparable to older generation replicating smallpox vaccinesDOI 10.1101/2022.09.07.22279689
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