Article

Analgesia effects of lappaconitine in leukemia bone pain in a mouse model

2015-04-09

Abstract excerpt

Bone pain is a common and severe symptom in cancer patients. The present study employed a mouse model of leukemia bone pain by injection K562 cells into tibia of mouse to evaluate the analgesia effects of Lappaconitine. Our results showed that the lappaconitine treatment at day 15, 17 and 19 could effectively reduce the spontaneous pain scoring values, restore reduced degree in the inclined-plate test induced by i...

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Literature Corpus work: c4b6bde8-6372-5d22-9b61-15866a02f083
DOI: 10.7287/peerj.preprints.971v1

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