Article

STING suppresses cancer pain via immune and neuronal modulation

2021-01-19

Abstract excerpt

Agonists of the innate immune regulator stimulator of interferon genes (STING) have shown great efficacy in promoting antitumor immunity in preclinical models, leading to their exploration in cancer immunotherapy trials. Patients with advanced stage cancers frequently suffer from severe pain as a result of bone metastasis and bone destruction, for which there is no efficacious treatment. Here, using multiple mouse...

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Literature Corpus work: 5f74b443-78b0-5161-a04a-d516a1d2c499
DOI: 10.1101/2021.01.18.426944

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