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A non-vesicular Argonaute protein is transmitted from nematode to mouse and is important for parasite survival

2025-04-01

Abstract excerpt

Argonautes are ancient proteins with well-characterised functions in cell-autonomous gene regulation and genome defense but less clear roles in non-cell-autonomous processes. Extracellular Argonautes have been reported across plants, animals and protozoa yet their biochemical and functional properties remain elusive. Here we demonstrate that an extracellular Argonaute (exWAGO) released by the rodent-infective para...

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Identifiers and source

Literature Corpus work
c4967b7a-05de-5a7c-b851-ad93d75273c3
DOI
10.1101/2025.04.01.646544
Open publication

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A non-vesicular Argonaute protein is transmitted from nematode to mouse and is important for parasite survivalDOI 10.1101/2025.04.01.646544
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