Article
A non-vesicular Argonaute protein is transmitted from nematode to mouse and is important for parasite survival
2025-04-01
Abstract excerpt
Argonautes are ancient proteins with well-characterised functions in cell-autonomous gene regulation and genome defense but less clear roles in non-cell-autonomous processes. Extracellular Argonautes have been reported across plants, animals and protozoa yet their biochemical and functional properties remain elusive. Here we demonstrate that an extracellular Argonaute (exWAGO) released by the rodent-infective para...
Topics
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- Insect Resistance and Genetics
- Insect symbiosis and bacterial influences
- Invertebrate Immune Response Mechanisms
- Mosquito-borne diseases and control
- Parasitic Infections and Diagnostics
- Parasitic infections in humans and animals
- Research on Leishmaniasis Studies
- Viral Infectious Diseases and Gene Expression in Insects
Identifiers and source
- Literature Corpus work
- c4967b7a-05de-5a7c-b851-ad93d75273c3
- DOI
- 10.1101/2025.04.01.646544
